Pathogenesis of ulcus cruris

Chronic Venous Insufficiency (CVI) with Ulcus Cruris

Chronic venous insufficiency (CVI) denotes the stages of chronic venous weakness in the lower extremities. According to Widmer, the following stages are defined, which can be passed through in the course of years, particularly if left untreated: I – corona phlebectatica, ankle edema; II – trophic skin lesions, dermatitis, hyperpigmentation, dermatoliposclerosis; IIIa – healed ulcus cruris venos...

Differential diagnosis of leg ulcers Differentialdiagnosen des Ulcus cruris

The Healing of Ulcus Cruris by Mesenchymal Stem Cells: No delay in wound healing by high-dose and standard chemotherapy

A 61-year-old male patient with T-cell NHL PTCL type (CD30-, Alk-), st. II.BE (oesophagus, mediastinum) was treated with 6 cycles of CHOP from June to October 2012. After the completion of 6 cycles, the CT images showed a mild progression of the disease. The patient received 2 cycles of ICE (ifosfamide, carboplatin, etoposide) (11-12/2012) + radiotherapy on mediastinum TD 30 Gy. After the secon...

Draft Genome Sequence of Pseudomonas aeruginosa Strain WS394, a Multidrug-Resistant and Highly Cytotoxic Wound Isolate from Chronic Ulcus Cruris

Pseudomonas aeruginosa is a frequent human pathogen that increasingly causes chronic infections of nonhealing wounds. Here we present the 6.8 Mb draft genome of strain WS394, a multidrug-resistant chronic ulcer isolate that exhibited outstanding high cell cytotoxicity despite defective secretion of exotoxin U, suggesting a habitat-dependent adaptation process.

Tinea Cruris